Update your browser for a better shopping experience!

Get faster load times, stronger security and access to all features.

Dramatically Different Moisturizing Lotion SPF50 75ml

Product code: T230485

This lightweight 75ml face moisturising lotion strengthens your skin's moisture barrier while providing crucial SPF50 protection without the white cast typically associated with sunscreens. Clinique's Dramatically Different formula works to hydrate and fortify skin through its proprietary lipid-mix technology and sunflower seed cake extract that actively reinforces the skin's natural barrier. The non-greasy texture absorbs quickly, allowing for seamless application beneath make-up or as a standalone treatment. Suitable for combination to dry skin types, this dual-action lotion provides both 8-hour moisture replenishment and broad-spectrum protection against harmful UVA/UVB rays that can lead to premature aging.

Dermatologist developed. Allergy tested. 100% fragrance free. Safe for sensitive skin. Skin-Strengthening Formula Strengthens skin’s barrier to help keep more moisture in and harmful irritants out. Instant and All-Day Hydration Delivers instant and all-day hydration, soothing skin in need of comfort. Leaves skin feeling soft, smooth, and supple. Replenishes skin’s oil-water balance for skin that feels healthier. Protects Against UV Rays Helps defend against skin-damaging UVA and UVB rays. Lightweight Formula Silky lotion slips on easily, absorbs quickly. Non-greasy. Doesn’t leave a white cast. Works well under makeup.

Dramatically Different Moisturizing Lotion SPF50 75ml

£38

£5.07 per 10ml

Free standard delivery over £75, otherwise from £3.99

Reviews (38)

4.8

18% Recommended this product

Mentions
21 September 2026Ma52
Verified Purchase

Ever reliable skin-care

Yes, I recommend this

Moisturiser combined with SPF50 protection is the perfect combination for fragile skin.

Reviewer Ratings

Quality

Excellent

Helpful?

Reviewer Ratings

Quality

Excellent

20 September 2026bruno2barram
Verified Purchase

Not brilliant

No, I don't recommend this

Not sure about this. Wanted an alternative to double serum/day cream/sun cream combo which felt quite heavy on skin. This ticked the boxes on paper. In reality it feels thin and watery. Can’t use over double serum as feels sticky. I will have to get a Clinique serum I think. On reading online you really need to reapply during the day so not as purse friendly as first thought. Ok on hands for sunspots. Seem to have dry skin around mouth now during the day. The Skin Kind from M&S sorts that out.

Reviewer Ratings

Quality

Average

Helpful?

Reviewer Ratings

Quality

Average

09 September 2026Annie 2B
Verified Purchase

Dramatically different, as the name states.

Yes, I recommend this

I had a sample of this moisturiser in the Summer bundle range. It is perfect for my complexion. In fact, I bought a full size one, I am so impressed. That was reduced so I was even happier.

Reviewer Ratings

Quality

Excellent

Helpful?

Reviewer Ratings

Quality

Excellent

06 September 2026Lindalivi
Verified Purchase

Reliably high quality

Yes, I recommend this

This is a lovely product, applies well, SPF is a huge bonus

Reviewer Ratings

Quality

Excellent

Helpful?

Reviewer Ratings

Quality

Excellent

05 September 2026nibs82
Verified Purchase

Great

Was advised to use a factor 50 as skin getting older. It’s lovely. Just on its own gives a lovely glow. Even better as can buy at Marks and with money off offer

Reviewer Ratings

Quality

Excellent

Helpful?

Reviewer Ratings

Quality

Excellent

11 July 2026Anflerow
Verified Purchase

Great product

Yes, I recommend this

I use this moisturiser all the time and having SPF is an added bonus in the hot weather

Helpful?

25 June 2026carolynb

At Last ! DDML with SPF!

Originally posted on Clinique UK

I've been using the original DDML for 30+ years (I'm 63) and was hoping for Clinique to reformulate with SPF I love this! I was worried incase it would cast a "white" film over my face but if blended in properly it doesn't! A much welcome addition to the DDM family!

Helpful?

14 June 2026Vivsteve
Verified Purchase

Lovely product.

Yes, I recommend this

Back to a product I like and great to be able to get it from M&S. Product suits my skin and give good protection.

Helpful?

11 June 2026HKEB

Simple but perfect

Originally posted on Clinique UK

Im 60 and I've been using clinique moisturisers exclusively for 35 years. I just tried this one and I love it. Clinique have taken its classic daily moisturiser and added factor 50 spf, its really all you need. IAdmittedly though I do use the serium and moisture surge too and the combo keeps my skin soft and hydrated all.day. I'd reccommend.

Helpful?

28 May 2026SusieMcAd
Verified Purchase

Super moisturiser with SPF50

After a stern warning from my GP, I was looking for a moisturiser with factor 50 UVA and UVB SPF, which was suitable for wearing under makeup. I have used Clinique products forever, and was delighted to find they make exactly this product in their Dramatically Different Moisturising lotion with SPF50. Lovely to use as ever, but with the added protection bonus. I would certainly recommend it.

Helpful?

23 May 2026MIFFLE
Verified Purchase

Great with SPF50!

Yes, I recommend this

Great on my normal skin. Want a daily moisturiser with SPF50! This is for you.

Reviewer Ratings

Quality

Excellent

Helpful?

Reviewer Ratings

Quality

Excellent

13 May 2026Busybee 22
Verified Purchase

Great product

I have used Clinique moisturiser for ever and wondered why it never had SPF added. Finally it does - at last. A little thicker than the original and although it doesn’t spread quite as easily it is my new go to!

Helpful?

25 April 2026Chez79

Irritated my skin

Originally posted on Clinique UK

I've always liked Clinique products but unfortunately I made the mistake of choosing this instead of the anti redness daily relief cream. I thought this would be the better option due to the SPF 50 and it claims to be suitable for sensitive skin. Sadly I've used it a few times now and it feels heavy and irritates my skin.

Helpful?

10 April 2026SKJAM
Verified Purchase

Repeat purchase

Love this product. Have to be very careful with my skin. Love the spf 50.

Reviewer Ratings

Quality

Excellent

Helpful?

Reviewer Ratings

Quality

Excellent

03 March 2026Anna

Lovely!

Originally posted on Clinique UK

I love this, only wish it came in the gel format as i have oilier skin so need to use it with powder.

Helpful?

22 February 2026HartleyGardener
Verified Purchase

Great product

I’ve used this product for years, it’s still the best moisturiser out there.

Reviewer Ratings

Quality

Excellent

Helpful?

Reviewer Ratings

Quality

Excellent

18 February 2026Buddha68
Verified Purchase

Great liquid moisturiser

Yes, I recommend this

This is a great moisturiser for me. I used to use it years ago, the one without a SPF, which is still a good option. As it is liquid, I find that I don’t need to use as much so it lasts longer than a cream moisturiser. This product is suitable for dry/combination and/or mature skin which mine is. I would recommend!

Reviewer Ratings

Quality

Excellent

Helpful?

Reviewer Ratings

Quality

Excellent

12 August 2025Vagas lady

Silky smooth and smells great

Originally posted on Clinique UK

Love this new moisturiser with spf 50 glides on and disappears into skin no tacky touch feels same as my original Dramatically Different + moisturiser lotion I love it hopefully will come in the big size

Helpful?

07 August 2025Rachel

Amazing New Day Cream!!!

Originally posted on Clinique UK

This SPF 50 is incredibly lightweight and absorbs quickly without leaving any white cast or grainy texture!!! It gives my skin a natural, healthy glow and works perfectly with my sensitive combination skin. Finally, a sunscreen that feels comfortable and looks great (even under make-up!).

Helpful?

04 August 2025Zazou

AFTER FOUR WEEKS TRIAL............ IT IS A YES

Originally posted on Clinique UK

My skin was not sure for the first few days.... it took a week to adapt. After four weeks trial it is definitely a yes - not greasy or marks. A really good finish on the skin all day even on full sunny days. Be careful with the eyes !!!

Helpful?

1 of 7